Quantitative single-cell physiology, and in particular the determinants and homeostatic effectors of cell growth, cell-cycle progression and the control of cell division.
Chromosome folding and dynamics.
Role of molecular crowding in chromosome organization and cell physiology.
Statistical invariants and functional profiling in evolutionary genomics and microbiome composition.
The evolutionary dynamics of major genome rearrangements, such as large-scale duplications, aneuploidy and changes in the replication program.