PhD Programme in Complex Systems for Life Sciences (until 35th cycle)

Selected research products

CD39/CD73 dysregulation and adenosine metabolism contribute to T cell immunosuppression in patients with Sézary syndrome
2023-01-01 Yakymiv, Yuliya; Marchisio, Sara; Ortolan, Erika; Bracci, Cristiano; Senetta, Rebecca; Rumore, Maria Rebecca; Tampieri, Cristian; Fia, Marianna; Ribero, Simone; Funaro, Ada; Quaglino, Pietro https://iris.unito.it/handle/2318/1885070

CD38 Expression by Circulating and Skin-Infiltrating Lymphocytes from Sezary Syndrome Patients: A Flow Cytometry and Immunohistochemistry Study
2022-01-01 Quaglino P.; Novelli M.; Fava P.; Ortolan E.; Astrua C.; Tonella L.; Tomasini C.F.; Senetta R.; Ribero S.; Ponti R.; Fierro M.T.; Funaro A. https://iris.unito.it/handle/2318/1858942

Sézary Syndrome: Different Erythroderma Morphological Features with Proposal for a Clinical Score System
2022-01-01 G. Roccuzzo, S. Giordano, G. Avallone, M. Rubatto, S. Canonico, A. Funaro, E. Ortolan, R. Senetta, P. Fava, M.T. Fierro, S. Ribero, P. Quaglino https://iris.unito.it/handle/2318/1844146

Increased expression of the ectoenzyme CD38 in peripheral blood plasmablasts and plasma cells of patients with systemic sclerosis.
2022-01-01 Agarbati S, Benfaremo D, Viola N, Paolini C, Svegliati Baroni S, Funaro A, Moroncini G, Malavasi F, Gabrielli A https://iris.unito.it/handle/2318/1885233

Flow-cytometry and functional evaluation of the CD39/CD73 adenosinergic immunosuppressive axis in patients with Sézary syndrome
2021-01-01 Pietro Quaglino, Ada Funaro, Erika Ortolan, Rebecca Senetta, Gianluca Avallone, Martina Merli, Cristiano Bracci, Maria Rebecca Rumore, Yuliya Yakymiv, Maria Teresa Fierro https://iris.unito.it/handle/2318/1844064

CD157 signaling promotes survival of acute myeloid leukemia cells and modulates sensitivity to cytarabine through regulation of anti-apoptotic Mcl-1.
2021-01-01 Yakymiv Y, Augeri S, Bracci C, Marchisio S, Aydin S, D'Ardia S, Massaia M, Ferrero E, Ortolan E, Funaro A. https://iris.unito.it/handle/2318/1816048

Expression, Functions and Potential Therapeutic Implications of CD157 in Acute Myeloid Leukemia
2020-01-01 Yuliya Yakymiv, Stefania Augeri, Cristiano Bracci, Erika Ortolan, Ada Funaro https://iris.unito.it/handle/2318/1755454

In vitro dexamethasone treatment does not induce alternative ATM transcripts in cells from Ataxia–Telangiectasia patients
2020-01-01 Pozzi E.; Giorgio E.; Mancini C.; Lo Buono N.; Augeri S.; Ferrero M.; Di Gregorio E.; Riberi E.; Vinciguerra M.; Nanetti L.; Bianchi F.T.; Sassi M.P.; Costanzo V.; Mariotti C.; Funaro A.; Cavalieri S.; Brusco A. https://iris.unito.it/handle/2318/1764210

CD157 reduces acutemyeloid leukemia cell sensitivity tocytarabine through upregulation of MCL-1 anti-apoptotic protein
2019-01-01 Yuliya Yakymiv, Stefania Augeri, Giulia Fissolo, Cristiano Bracci, Silvia Peola, Stefano D’Ardia, Sembra Aydin, Massimo Massaia, Erika Ortolan, Ada Funaro. https://iris.unito.it/handle/2318/1714689

CD157 REGULATES THE SENSITIVITY OF ACUTE MYELOID LEUKEMIA CELLS TO CHEMOTHERAPY BY MODULATING THE APOPTOTIC RESPONSE
2019-01-01 Yuliya Yakymiv, Stefania Augeri, Giulia Fissolo, Cristiano Bracci, Silvia Peola, Stefano D’Ardia, Semra Aydin, Massimo Massaia, Erika Ortolan, Ada Funaro. https://iris.unito.it/handle/2318/1714692

CD157: From immunoregulatory protein to potential therapeutic target
2019-01-01 Erika Ortolan, Stefania Augeri, Giulia Fissolo, Irene Musso, Ada Funaro https://iris.unito.it/handle/2318/1695398

CD157: From Myeloid Cell Differentiation Marker to Therapeutic Target in Acute Myeloid Leukemia.
2019-01-01 Yuliya Yakymiv, Stefania Augeri, Giulia Fissolo, Silvia Peola, Cristiano Bracci, Monica Binaschi, Daniela Bellarosa, Andrea Pellacani, Enza Ferrero, Erika Ortolan, Ada Funaro https://iris.unito.it/handle/2318/1719287

Soluble CD157 in pleural effusions: a complementary tool for the diagnosis of malignant mesothelioma
2018-01-01 Stefania Augeri , Stefania Capano , Simona Morone , Giulia Fissolo , Alice Giacomino , Silvia Peola , Zahida Drace , Ida Rapa , Silvia Novello , Marco Volante , Luisella Righi , Enza Ferrero , Erika Ortolan, Ada Funaro https://iris.unito.it/handle/2318/1665672

Human canonical CD157/Bst1 is an alternatively spliced isoform masking a previously unidentified primate-specific exon included in a novel transcript
2017-01-01 Ferrero, Enza; Lo Buono, Nicola; Morone, Simona; Parrotta, Rossella; Mancini, Cecilia; Brusco, Alfredo; Giacomino, Alice; Augeri, Stefania; Rosal-Vela, Antonio; García-Rodríguez, Sonia; Zubiaur, Mercedes; Sancho, Jaime; Fiorio Pla, Alessandra; Funaro, Ada https://iris.unito.it/handle/2318/1654379

CD157 contributes to the environment-mediated chemoresistance in acute myeloid leukemia
2017-01-01 Stefania Augeri, Stefano D'Ardia, Semra Aydin, Chiara Dal Secco, Erika Ortolan, Ada Funaro https://iris.unito.it/handle/2318/1797253

Acute myeloid leukemia: CD157 under the spotlight
2017-01-01 Stefania Augeri, Simona Morone, Stefano D’Ardia, Semra Aydin, Erika Ortolan, Ada Funaro https://iris.unito.it/handle/2318/1797258

One gene, two proteins: alternative splicing in human CD157/Bst1 unmasked
2017-01-01 Ferrero Enza, Lo Buono Nicola, Morone Simona, Parrotta Rossella, Giacomino Alice, Augeri Stefania, Mancini Cecilia, Rosal-Vela Antonio, Garcia-Rodriguez Sonia, Zubiaur Mercedes, Sancho Jaime, Ortolan Erika, Funaro Ada https://iris.unito.it/handle/2318/1797255

Development of a novel epitope-based diagnostic assay for systemic sclerosis
2017-01-01 Moroncini, G ; Mozzicafreddo, M ; Cuccioloni, M ; Grieco, A ; Paolini, C ; Tonnini, C ; Avvedimento,; Salvucci, S ; Funaro, A ; Gabrielli, A https://iris.unito.it/handle/2318/1677998

Characterization of binding and quantification of human autoantibodies to PDGFRα using a biosensor-based approach
2017-01-01 Moroncini, Gianluca; Cuccioloni, Massimiliano; Mozzicafreddo, Matteo; Pozniak, Katarzyna Natalia; Grieco, Antonella; Paolini, Chiara; Tonnini, Cecilia; Spadoni, Tatiana; Svegliati, Silvia; Funaro, Ada; Angeletti, Mauro; Gabrielli, Armando https://iris.unito.it/handle/2318/1633831

Agonistic Anti-PDGF Receptor Autoantibodies from Patients with Systemic Sclerosis Impact Human Pulmonary Artery Smooth Muscle Cells Function In Vitro
2017-01-01 Svegliati, Silvia; Amico, Donatella; Spadoni, Tatiana; Fischetti, Colomba; Finke, Doreen; Moroncini, Gianluca; Paolini, Chiara; Tonnini, Cecilia; Grieco, Antonella; Rovinelli, Marina; Funaro, Ada; Gabrielli, Armando https://iris.unito.it/handle/2318/1633760

Induction of Scleroderma Fibrosis in Skin-Humanized Mice by Administration of Anti−Platelet-Derived Growth Factor Receptor Agonistic Autoantibodies
2016-01-01 Luchetti, Michele M.; Moroncini, Gianluca; Jose Escamez, Maria; Svegliati Baroni, Silvia; Spadoni, Tatiana; Grieco, Antonella; Paolini, Chiara; Funaro, Ada; Avvedimento, Enrico V.; Larcher, Fernando; Del Rio, Marcela; Gabrielli, Armando https://iris.unito.it/handle/2318/1591708

Adult-onset autosomal recessive ataxia associated with neuronal ceroid lipofuscinosis type 5 gene (CLN5) mutations.
2015-01-01 Mancini C;Nassani S;Guo Y;Chen Y;Giorgio E;Brussino A;Di Gregorio E;Cavalieri S;Lo Buono N;Funaro A;Pizio NR;Nmezi B;Kyttala A;Santorelli FM;Padiath QS;Hakonarson H;Zhang H;Brusco A https://iris.unito.it/handle/2318/153157

Epitope specificity determines pathogenicity and detectability of anti-platelet-derived growth factor receptor α autoantibodies in systemic sclerosis
2015-01-01 Moroncini, Gianluca; Grieco, Antonella; Nacci, Giulia; Paolini, Chiara; Tonnini, Cecilia; Pozniak, Katarzyna N.; Cuccioloni, Massimiliano; Mozzicafreddo, Matteo; Svegliati, Silvia; Angeletti, Mauro; Kazlauskas, Andrius; Avvedimento, Enrico V.; Funaro, Ada; Gabrielli, Armando https://iris.unito.it/handle/2318/1521840

CD157/BST1 regulates cell adhesion and spreading through the interaction with the heparin-binding domains of fibronectin
2014-01-01 S. Augeri; S. Morone; M. Cuccioloni; M. Mozzicafreddo; M. Angeletti; N. Lo Buono; A. Giacomino; E. Ortolan; A. Funaro https://iris.unito.it/handle/2318/157733

CD157: A New Prognostic and/or Predictive Marker in Ovarian Cancer? A Retrospective Study
2014-01-01 Lanzo G; Borghese G; Arisio R; Katsaros D; Volante M; Rapa I; Benedetto C; Ortolan E; Funaro A. https://iris.unito.it/handle/2318/148161

CD157 at the intersection between leukocyte trafficking and epithelial ovarian cancer invasion.
2014-01-01 Lo Buono N; Morone S; Giacomino A; Parrotta R; Ferrero E; Malavasi F; Ortolan E; Funaro A https://iris.unito.it/handle/2318/143381

Binding of CD157 protein to fibronectin regulates cell adhesion and spreading
2014-01-01 S. Morone; S. Augeri; M. Cuccioloni; M. Mozzicafreddo; M. Angeletti; N. Lo Buono; A. Giacomino; E. Ortolan; A. Funaro https://iris.unito.it/handle/2318/148160

CD157 enhances malignant pleural mesothelioma aggressiveness and predicts poor clinical outcome.
2014-01-01 Ortolan E; Giacomino A; Martinetto F; Morone S; Lo Buono N; Ferrero E; Scagliotti G; Novello S; Orecchia S; Ruffini E; Rapa I; Righi L; Volante M; Funaro A https://iris.unito.it/handle/2318/148159

The ADP-ribosyl cyclases - the current evolutionary state of the ARCs
2014-01-01 Ferrero E; Lo Buono N; Horenstein AL; Funaro A; Malavasi F. https://iris.unito.it/handle/2318/157979

CD157: A NEW PROGNOSTIC MARKER IN OVARIAN CANCER
2014-01-01 G. Borghese; G. Lanzo; R. Benvenuto; R. Arisio; D. Katsaros; M. Volante; I. Rapa; E. Ortolan; C. Benedetto; A. Funaro https://iris.unito.it/handle/2318/157748

ELOVL5 Mutations Cause Spinocerebellar Ataxia 38
2014-01-01 Eleonora Di Gregorio;Barbara Borroni;Elisa Giorgio;Daniela Lacerenza;Marta Ferrero;Nicola Lo Buono;Neftj Ragusa;Cecilia Mancini;Marion Gaussen;Alessandro Calcia;Nico Mitro;Eriola Hoxha;Isabella Mura;Domenico A. Coviello;Young-Ah Moon;Christelle Tesson;Giovanna Vaula;Philippe Couarch;Laura Orsi;Eleonora Duregon;Mauro Giulio Papotti;Jean-François Deleuze;Jean Imbert;Chiara Costanzi;Alessandro Padovani;Paola Giunti;Marcel Maillet-Vioud;Alexandra Durr;Alexis Brice;Filippo Tempia;Ada Funaro;Loredana Boccone;Donatella Caruso;Giovanni Stevanin;Alfredo Brusco https://iris.unito.it/handle/2318/151050

Genome-wide expression profiling and functional characterization of SCA28 lymphoblastoid cell lines reveal impairment in cell growth and activation of apoptotic pathways.
2013-01-01 MANCINI C.; Roncaglia P; Brussino A; Stevanin G; Lo Buono N; Krmac H; Maltecca F; Gazzano E; Bartoletti Stella A; Calvaruso MA; Iommarini L; Cagnoli C; Forlani S; Le Ber I; Durr A; Brice A; Ghigo D; Casari G; Porcelli AM; Funaro A; Gasparre G; Gustincich S; Brusco A. https://iris.unito.it/handle/2318/143411

Genome-wide expression analysis identified defects in cell growth, proliferation and viability in SCA28 lymphoblastoid cell lines.
2013-01-01 Mancini C; Roncaglia P; Brussino A; Stevanin G; Lo Buono N; Krmac H; Maltecca F; Gazzano E; Bartoletti Stella A.; Calvaruso M.A.; Iommarini L.; Cagnoli C.; Forlani S; Le Ber I; Durr A; Brice A; Ghigo D; Casari G; Porcelli AM; Funaro A; Gasparre G; Gustincich S; Brusco A https://iris.unito.it/handle/2318/143407

CD38 and CD157: A long journey from activation markers to multifunctional molecules.
2013-01-01 Quarona V;Zaccarello G;Chillemi A;Brunetti E;Singh VK;Ferrero E;Funaro A;Horenstein AL;Malavasi F https://iris.unito.it/handle/2318/134656

Genome-wide expression profiling and functional characterization of SCA28 lymphoblastoid cell lines reveal impairment in cell growth and activation of apoptotic pathways
2013-01-01 Cecilia Mancini;Paola Roncaglia;Alessandro Brussino;Giovanni Stevanin;Nicola Lo Buono;Helena Krmac;Francesca Maltecca;Elena Gazzano;Anna Bartoletti Stella;Maria Calvaruso;Luisa Iommarini;Claudia Cagnoli;Sylvie Forlani;Isabelle Le Ber;Alexandra Durr;Alexis Brice;Dario Ghigo;Giorgio Casari;Anna Porcelli;Ada Funaro;Giuseppe Gasparre;Stefano Gustincich;Alfredo Brusco https://iris.unito.it/handle/2318/140901

Biosensor-based Binding Assay for Platelet-Derived Growth Factor Receptor-α Autoantibodies in Human Serum
2013-01-01 M. Cuccioloni; G. Moroncini; M. Mozzicafreddo; K.N. Pozniak; G. Nacci; A. Grieco; C. Paolini; C. Tonnini; A. Funaro; M. Angeletti; A. Gabrielli https://iris.unito.it/handle/2318/142222

A NOVEL GENE FOR SPINOCEREBELLAR ATAXIA (SCA) LINKED TO CHROMOSOME 6 AND INVOLVED IN FATTY ACID METABOLISM
2013-01-01 Eleonora Di Gregorio; Barbara Borroni; Elisa Giorgio; Daniela Lacerenza; Cecilia Mancini; Alessandro Calcia; Isabella Mura; Domenico Coviello; Nico Mitro; Marion Gaussen; Nicola Lo Buono; Ada Funaro; Giovanna Vaula; Isabelle Lagroua; Laura Orsi; Alexandra Durr; Chiara Costanzi; Alessandro Padovani; Alexis Brice; Loredana Boccone; Eriola Hoxha; Filippo Tempia; Donatella Caruso; Giovanni Stevanin; Alfredo Brusco https://iris.unito.it/handle/2318/143385

A NOVEL GENE FOR SPINOCEREBELLAR ATAXIA (SCA) LINKED TO CHROMOSOME 6 AND FATTY ACID METABOLISM
2013-01-01 Eleonora Di Gregorio; Barbara Borroni; Elisa Giorgio; Daniela Lacerenza; Cecilia Mancini; Alessandro Calcia; Isabella Mura; Domenico Coviello; Nico Mitro; Marion Gaussen; Nicola Lo Buono; Ada Funaro; Giovanna Vaula; Isabelle Lagroua; Laura Orsi; Alexandra Durr; Chiara Costanzi; Alessandro Padovani; Alexis Brice; Loredana Boccone; Eriola Hoxha; Filippo Tempia; Donatella Caruso; Giovanni Stevanin; Alfredo Brusco https://iris.unito.it/handle/2318/143387

Biological role, clinical significance and potential therapeutic applications of CD157 in ovarian cancer
2013-01-01 S. Morone; N. Lo Buono; A. Giacomino; R. Parrotta; R. Arisio; D. Katsaros; N. Biglia; G. Chiorino; I. Rapa; M. Volante; E. Ortolan; A. Funaro https://iris.unito.it/handle/2318/142286

A NOVEL GENE FOR SPINOCEREBELLAR ATAXIA (SCA) LINKED TO CHROMOSOME 6 AND INVOLVED IN FATTY ACID METABOLISM
2013-01-01 Eleonora Di Gregorio; Barbara Borroni; Elisa Giorgio; Daniela Lacerenza; Cecilia Mancini; Alessandro Calcia; Isabella Mura; Domenico Coviello; Nico Mitro; Marion Gaussen; Nicola Lo Buono; Ada Funaro; Giovanna Vaula; Isabelle Lagroua; Laura Orsi; Alexandra Durr; Chiara Costanzi; Alessandro Padovani; Alexis Brice; Loredana Boccone; Eriola Hoxha; Filippo Tempia; Donatella Caruso; Giovanni Stevanin; Alfredo Brusco https://iris.unito.it/handle/2318/143386

CD157-extracellular matrix proteins interactions enhance integrin-mediated signalling cascade in monocytes
2013-01-01 S. Morone; A. Giacomino; R. Parrotta; N. Lo Buono; M. Cuccioloni; E. Ortolan; A. Funaro https://iris.unito.it/handle/2318/157769

Ectoenzymes in epithelial ovarian carcinoma: potential diagnostic markers and therapeutic targets
2012-01-01 N. Lo Buono; S. Morone; R. Parrotta; A. Giacomino; E. Ortolan; A. Funaro https://iris.unito.it/handle/2318/111008

Overexpression of CD157 contributes to epithelial ovarian cancer progression by promoting mesenchymal differentiation
2012-01-01 S. Morone; N. Lo Buono; R. Parrotta; A. Giacomino; G. Nacci; A. Brusco; A. Larionov; P. Ostano; M. Mello-Grand; G. Chiorino; E. Ortolan; A. Funaro https://iris.unito.it/handle/2318/120890

AUTOIMMUNITY TO PDGFR: A RELEVANT PATHOGENIC LINK IN SSc
2012-01-01 G. Moroncini; A. Grieco; C. Paolini; G. Nacci; K. Pozniak; S. Mori; D. Finke; M. Cuccioloni; M. Mozzicafreddo; C. Tonnini; S. Svegliati; M. Angeletti; E. Avvedimento; A. Funaro; A. Gabrielli https://iris.unito.it/handle/2318/120952

Studio dei meccanismi patogenetici dell’Atassia Spinocerebellare 28.
2012-01-01 Mancini C.; Roncaglia P.; Lo Buono N.; Gazzano E.; Brussino A.; Cagnoli C.; Krmac H.; Stevanin G.; Forlani S.; Hoxha E.; Funaro A.; Durr A.; Tempia F.; Altruda F.; Turco E.; Ghigo D.; Gustincich S.; Brusco A. https://iris.unito.it/handle/2318/143406

Identification of pathogenic mechanisms of Spinocerebellar Ataxia, type 28 (SCA28).
2012-01-01 MANCINI C.; Roncaglia P; Lo Buono N; Gazzano E; Bartoletti Stella A; Mariani E; Calvaruso M; Iommarini L; Brussino A; Cagnoli C.; Krmac H; Stevanin G; Forlani S; Funaro A; Durr A; Porcelli A; Ghigo D; Gasparre G; Gustincich S; Brusco A https://iris.unito.it/handle/2318/143408

Epitopes of the human PDGF receptor able to bind human auto-antibodies, antibodies and thereof.
2012-01-01 G.L. Moroncini; A. Funaro; A. Gabrielli; E.V. Avvedimento; S. Svegliati-Baroni; M. Santillo; R. Paternò. https://iris.unito.it/handle/2318/119889

Studio dei meccanismi patogenetici dell’Atassia Spinocerebellare tipo 28.
2012-01-01 MANCINI C.; Roncaglia P; Lo Buono N; Gazzano E; Bartoletti Stella A; Mariani E; Calvaruso M; Iommarini L; Brussino A; Cagnoli C.; Krmac H; Stevanin G; Forlani S; Funaro A; Durr A; Porcelli A; Ghigo D; Gasparre G; Gustincich S; Brusco A. https://iris.unito.it/handle/2318/143409

Development of a conformation-dependent immunoassay for the diagnosis of systemic sclerosis
2012-01-01 Pozniak K; Nacci G; Grieco A; Paolini C; Mori S; Tonini C; Cuccioloni M; Mozzicafreddo M; Angeletti M; Funaro A; Gabrielli A; Moroncini G. https://iris.unito.it/handle/2318/123432

Involvement of CD157 in the control of ovarian cancer progression
2012-01-01 N. Lo Buono; S. Morone; R. Parrotta; A. Giacomino; G. Chiorino; P. Ostano; E. Ferrero; M. Volante; A. Funaro; E. Ortolan https://iris.unito.it/handle/2318/118582

CD157 is a novel prognostic marker of malignant pleural mesothelioma involved in the control of tumor aggressiveness
2012-01-01 A. Giacomino; S. Morone; R. Parrotta; N. Lo Buono; I. Rapa; L. Righi; M. Volante; E. Ruffini; E. Ortolan; A. Funaro https://iris.unito.it/handle/2318/118454

Restricted immunoglobulin repertoire and evolutionary mechanism of PDGFR-autoreactive memory B cells in systemic sclerosis
2012-01-01 Moroncini G; Paolini C; Grieco A; Nacci G; Tonnini C; Svegliati S; Pozniak K; Avvedimento E; Funaro A; Gabrielli A https://iris.unito.it/handle/2318/126378

Clinical and biological significance of CD157 in malignant pleural mesothelioma
2011-01-01 S. Morone; E. Ortolan; A. Giacomino; R. Parrotta; N. Lo Buono; I. Rapa; L. Righi; M. Volante; E. Ruffini; S. Demichelis; G. Rovere; S. Novello; F. Malavasi; A. Funaro. https://iris.unito.it/handle/2318/119913

Biological role and clinical significance of CD157 in epithelial ovarian cancer
2011-01-01 Nicola, Lo Buono; Rossella, Parrotta; Riccardo, Arisio; Dyonissios, Katsaros; Ida, Rapa; Enza, Ferrero; Marco, Volante; Erika, Ortolan; Ada, Funaro https://iris.unito.it/handle/2318/1533506

The CD157-integrins partnership orchestrates human monocyte adhesion and transendothelial migration
2011-01-01 R. Parrotta; N. Lo Buono; S. Morone; A. Giacomino; P. Bovino; G. Nacci; E. Ortolan; E. Ferrero; F. Malavasi; A. Funaro https://iris.unito.it/handle/2318/91277

8-Oxoguanine DNA-glycosylase repair activity and expression: a comparison between cryopreserved isolated lymphocytes and EBV-derived lymphoblastoid cell lines
2011-01-01 Mazzei F; Guarrera S; Allione A; Simonelli V; Narciso L; Barone F; Minoprio A; Ricceri F; Funaro A; D'Errico M; Vogel U; Matullo G; Dogliotti E https://iris.unito.it/handle/2318/80185

CD157 expression enhances invasiveness of ovarian cancer cells and induces a mesenchymal phenotype
2011-01-01 N. Lo Buono; M. Scianna; P. Bovino; S. Morone; R. Parrotta; E. Ferrero; C. Giverso; L. Preziosi; F. Malavasi; A. Funaro; E. Ortolan. https://iris.unito.it/handle/2318/93317

The CD157-integrin partnership controls transendothelial migration and adhesion of human monocytes.
2011-01-01 Lo Buono N; Parrotta R; Morone S; Bovino P; Nacci G; Ortolan E; Horenstein AL; Inzhutova A; Ferrero E; Funaro A https://iris.unito.it/handle/2318/89518

Isolation and cloning of stimulatory anti-PDGF receptor auto-antibodies from the immunological repertoire of patients with systemic sclerosis
2011-01-01 G. Nacci; G. Moroncini; A. Grieco; C. Paolini; M. Cuccioloni; M. Mozzicafreddo; K. Pozniak; C. Tonnini; S. Svegliati; M. Angeletti; E. Avvedimento; A. Funaro; A. Gabrielli https://iris.unito.it/handle/2318/91952

A Genome-wide Expression profiling to unravel effect of missense mutations in SCA28 patients
2011-01-01 Mancini C; Roncaglia P; Lo Buono N; Brussino A; Cagnoli C; Maltecca F; Krmac H; Limongi T; Stevanin G; Forlani S; Casari G; Funaro A; Durr A; Migone N; Gustincich S; Brusco A https://iris.unito.it/handle/2318/97020

Mutation Analysis of the LH Receptor Gene in Leydig Cell Adenoma and Hyperplasia and Functional and Biochemical Studies of Activating Mutations of the LH Receptor Gene.
2011-01-01 Boot AM; Lumbroso S; Verhoef-Post M; Richter-Unruh A; Looijenga LH; Funaro A; Beishuizen A; van Marle A; Drop SL; Themmen AP https://iris.unito.it/handle/2318/92332

PDGF receptor as therapeutic and diagnostic target in Systemic sclerosis
2011-01-01 G. Moroncini; A. Grieco; G. Nacci; C. Paolini; M. Cuccioloni; M. Mozzicafreddo; K. Pozniak; E. Bracci; C. Tonnini; S. Svegliati; M. Angeletti; E. Avvedimento; A. Funaro; A. Gabrielli https://iris.unito.it/handle/2318/119835

Clinical and biological significance of CD157 in ovarian carcinoma
2011-01-01 E. Ortolan; N. Lo Buono; S. Morone; R. Parrotta; R. Arisio; D. Katsaros; I. Rapa; E. Ferrero; M. Volante; A. Funaro https://iris.unito.it/handle/2318/93316

Re: CD157 in ovarian carcinoma: How does it help us?
2010-01-01 Ortolan E; Ferrero E; Funaro A. https://iris.unito.it/handle/2318/82249

Development of a solid phase binding assay for the detection of conformational anti-PDGFR autoantibodies in the serum of patients affected by scleroderma
2010-01-01 G. Moroncini; G. Nacci; M. Cuccioloni; C. Paolini; A. Grieco; C. Tonnini; E.V. Avvedimento; A. Funaro; A. Gabrielli https://iris.unito.it/handle/2318/92722

Limiti penali alla libertà di manifestazione del pensiero nel codice penale cinese
2010-01-01 M. PELISSERO https://iris.unito.it/handle/2318/1642249

Functional Role and Prognostic Significance of CD157 in Ovarian Carcinoma
2010-01-01 Erika Ortolan; Riccardo Arisio; Simona Morone; Paola Bovino; Nicola Lo-Buono; Giulia Nacci; Rossella Parrotta; Dionyssios Katsaros; Ida Rapa; Giuseppe Migliaretti; Enza Ferrero; Marco Volante; Ada Funaro https://iris.unito.it/handle/2318/74541

PDGF receptor as therapeutic and diagnostic target in systemic sclerosis
2010-01-01 Moroncini G; Paolini C; Grieco A; Nacci G; Cuccioloni M; Mozzicafreddo M; Tonnini C; Svegliati S; Angeletti M; Avvedimento E; Funaro A; Gabrielli A https://iris.unito.it/handle/2318/125294

Unsuitability of lymphoblastoid cell lines as surrogate of cryopreserved isolated lymphocytes for the analysis of DNA double-strand break repair activity
2010-01-01 Zijno A; Porcedda P; Saini F; Allione A; Garofalo B; Marcon F; Guarrera S; Turinetto V; Minieri V; Funaro A; Crebelli R; Giachino C; Matullo G https://iris.unito.it/handle/2318/72891

Lymphoblastoid cell lines and cryopreserved isolated lymphocytes do not correlate for gamma-rays-induced chromosome damage and double strand break repair
2009-01-01 P Porcedda; A Zijno; F Saini; A Allione; B Garofalo; F Marcon; S Guarrera; V Turinetto; V Minieri; A Funaro; R Crebelli; C Giachino; G Matullo https://iris.unito.it/handle/2318/81584

Antibodies against Human Cytomegalovirus (HCMV)
2009-01-01 A. Funaro; G. Gribaudo; S. Landolfo https://iris.unito.it/handle/2318/56954

CD157 CONTROLS PERITONEAL DISSEMINATION AND INVASION OF OVARIAN CARCINOMA AND IS A MOLECULAR PREDICTOR OF POOR CLINICAL OUTCOME
2009-01-01 P. Bovino; E. Ortolan; S. Morone; N. Lo-Buono; R. Parrotta; M. El-Baroudi; I. Rapa; M. Volante; E. Ferrero; D. Katsaros; R. Arisio; F. Malavasi; A. Funaro https://iris.unito.it/handle/2318/119442

Antibodies against Human Cytomegalovirus (HCMV)
2009-01-01 FUNARO A; GRIBAUDO G; LANDOLFO S https://iris.unito.it/handle/2318/56295

Cloning of agonistic autoantibodies specific for the PDGF receptor from the B-cell repertoire of SSc patients
2009-01-01 G. Moroncini; G. Nacci; C. Paolini; A. Grieco; S. Svegliati Baroni; E. Ortolan; C. Tonnini; E. V. Avvedimento; A. Funaro; A. Gabrielli https://iris.unito.it/handle/2318/117575

Functional role of CD157 in monocyte migration
2009-01-01 R. Parrotta; N. Lo Buono; P. Bovino; S. Morone; M. El Baroudi; E. Ortolan; F. Malavasi; A. Funaro https://iris.unito.it/handle/2318/120183

Receptor activities of human CD157 in myeloid cells rely on the MAP-kinase signaling cascade
2008-01-01 N. Lo Buono; R. Parrotta; P. Bovino; S. Morone; E. Ortolan; F. Malavasi; A. Funaro https://iris.unito.it/handle/2318/117791

Antibodies against Human Cytomegalovirus (HCMV)
2008-01-01 FUNARO A; GRIBAUDO G; LANDOLFO S https://iris.unito.it/handle/2318/34952

Generation of potent neutralizing human monoclonal antibodies against cytomegalovirus infection from immune B cells
2008-01-01 A. Funaro; G. Gribaudo; A. Luganini; E. Ortolan; N. Lo Buono; E. Vicenzi; L. Cassetta; S. Landolfo; R. Buick; L. Falciola; M. Murphy; G. Garotta; F. Malavasi https://iris.unito.it/handle/2318/55902

Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology
2008-01-01 F. MALAVASI; S. DEAGLIO; A. FUNARO; E. FERRERO; A.L. HORENSTEIN ; E. ORTOLAN; T. VAISITTI; S. AYDIN https://iris.unito.it/handle/2318/35642

Large Genomic Mutations within the ATM Gene Detected by MLPA, Including a Duplication of 41 kb from Exon 4 to 20
2008-01-01 CAVALIERI S; FUNARO A; PAPPI P; MIGONE N; GATTI RA; BRUSCO A https://iris.unito.it/handle/2318/34299

Methods for obtaining immortalized antibody secreting cells
2007-01-01 FUNARO A; GAROTTA G; MURPHY M https://iris.unito.it/handle/2318/26249

The low density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus
2007-01-01 MOLINA S; CASTET V; FOURNIER-WIRTH C; PICHARD-GARCIA L; AVNER R; HARATS D; ROITELMAN J; BARBARAS R; GRABER P; GHERSA P; SMOLARSKY M; FUNARO A; MALAVASI F; LARREY D; COSTE J; FABRE JM; SA-CUNHA A; MAUREL P. https://iris.unito.it/handle/2318/38544

Stimulatory auto-antibodies to the Pdgf receptor as pathology marker and therapeutic target
2007-01-01 AVVEDIMENTO V.E.; GABRIELLI A.; SANTILLO M.; FUNARO A.; LUCHETTI M.; SVEGLIATI BARONI S. https://iris.unito.it/handle/2318/58366

CD157 is part of a supramolecular complex with CD11b/CD18 on the human neutrophil cell surface
2007-01-01 LAVAGNO L; FERRERO E; ORTOLAN E; MALAVASI F; FUNARO A https://iris.unito.it/handle/2318/37034

CD157 plays a pivotal role in neutrophil transendothelial migration
2006-01-01 ORTOLAN E; TIBALDI EV; FERRANTI B; LAVAGNO L; GARBARINO G; NOTARO R; LUZZATTO L; MALAVASI F; FUNARO A https://iris.unito.it/handle/2318/37667

Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis.
2006-01-01 BARONI SS; SANTILLO M; BEVILACQUA F; LUCHETTI M; SPADONI T; MANCINI M; FRATICELLI P; SAMBO P; FUNARO A; KAZLAUSKAS A; AVVEDIMENTO EV; GABRIELLI A. https://iris.unito.it/handle/2318/39748

CD38 and CD157 as receptors of the immune system: a bridge between innate and adaptive immunity
2006-01-01 MALAVASI F; DEAGLIO S; FERRERO E; FUNARO A; SANCHO J; AUSIELLO CM; ORTOLAN E; VAISITTI T; ZUBIAUR M; FEDELE G; AYDIN S; TIBALDI EV; DURELLI I; LUSSO R; CORNO F; HORENSTEIN AL https://iris.unito.it/handle/2318/36336

ATM mutations in Italian families with ataxia telangiectasia include two distinct large genomic deletions
2006-01-01 Cavalieri, Simona; Funaro, Ada; Porcedda, Paola; Turinetto, Valentina; Migone, Nicola; Gatti, Richard; Brusco, Alfredo https://iris.unito.it/handle/2318/29107

CD157 plays a pivotal role in neutrophil transendothelial migration
2006-01-01 E. Ortolan; E.V. Tibaldi; L. Lavagno; G. Garbarino; F. Malavasi; A. Funaro https://iris.unito.it/handle/2318/121332

Isolation of agonistic autoantibodies specific for the PDGF receptor from the B cell repertoire of SSC patients.
2006-01-01 G. Moroncini; S. Svegliati-Baroni; E. Ortolan; M. Mancini; M. Luchetti; C.Tonnini; E.V. Avvedimento; A. Funaro; A. Gabrielli https://iris.unito.it/handle/2318/121826

Use of genetic immunization to raise antibodies recognizing toxin-related cell surface ADP-ribosyltransferases in native conformation
2005-01-01 KOCH-NOLTE F; GLOWACKI G; BANNAS P; BRAASCH F; DUBBERKE G; ORTOLAN E; FUNARO A; MALAVASI F; HAAG F https://iris.unito.it/handle/2318/36703

CD157 plays a prominent role in neutrophil physiology
2005-01-01 E. Ortolan; B. Ferranti; L. Lavagno; E. Tibaldi; G. Garbarino; L. Luzzatto; F. Malavasi; A. Funaro https://iris.unito.it/handle/2318/6426

A panel of monoclonal antibodies recognizing GPI-anchored ADP-ribosyltransferase ART4, the carrier of the Dombrock blood group antigens
2005-01-01 PARUSEL I; KAHL S; BRAASCH F; GLOWACKI G; HALVERSON GR; REID ME; SCHAWALDER A; ORTOLAN E; FUNARO A; MALAVASI F; HARDIE D; HALDER S; BUCKLEY CD; HAAG F; KOCH-NOLTE F https://iris.unito.it/handle/2318/29481

CD157 is an important mediator of neutrophil adhesion and migration
2004-01-01 FUNARO A; ORTOLAN E; FERRANTI B; GARGIULO L; NOTARO R; LUZZATTO L; MALAVASI F. https://iris.unito.it/handle/2318/37299

Impairment of in vitro migration of neutrophils from patients with paroxysmal nocturnal hemoglobinuria (PNH).
2003-01-01 E. Ortolan; A. Funaro; B. Ferranti; L. Gargiulo; R. Notaro; L. Luzzatto; F. Malavasi. https://iris.unito.it/handle/2318/122232

Role of CD157 in the regulation of chemotaxis by human granulocytes
2003-01-01 A. Funaro; B. Ferranti; E. Ortolan; A.L. Horenstein; K. Ishihara; T. Hirano; F. Malavasi https://iris.unito.it/handle/2318/125899

Design and scaleup of downstream processing of monoclonal antibodies for cancer therapy: from research to clinical proof of principle.
2003-01-01 HORENSTEIN AL; CRIVELLIN F; FUNARO A; SAID M; MALAVASI F https://iris.unito.it/handle/2318/43140

Insulin modulates PC-1 processing and recruitment in cultured human cells.
2003-01-01 MENZAGHI C ;DI PAOLA R ;BAJ G ;FUNARO A ;ARNULFO A ;ERCOLINO T ;SURICO N ;MALAVASI F ;TRISCHITTA V https://iris.unito.it/handle/2318/29566

Courses

• Molecular basis of the interaction between tumor cells and the surrounding microenvironment in acute myeloid leukemia and multiple myeloma. Instructor prof. Ada Funaro
  Programma MD-PhD della Scuola di Medicina

Research topics

Per maggiori dettagli è possibile consultare la pagina del Docente sul sito del Dottorato in Sistemi Complessi per le Scienze della Vita

Gruppi di ricerca

Immunogenetica

Academic bodies

• Junta

Office hours

Previo appuntamento telefonico o via e.mail

Faculty