- Oggetto:
- Oggetto:
Introduction to Genomics
- Oggetto:
Academic year 2017/2018
- Course ID
- SCSV1-11-12
- Teacher
- Prof. Michele De Bortoli (Titolare del corso)
- Year
- 1° anno
- Credits/Recognition
- 10 cfu
- Course disciplinary sector (SSD)
- BIO/11 - biologia molecolare
- Delivery
- NA
- Language
- Italiano
- Attendance
- NA
- Type of examination
- NA
- Oggetto:
Sommario del corso
- Oggetto:
Course objectives
Introduction to Molecular Biology and Functional Genomics. Students should have an overview of the fundamental molecular mechanisms of DNA Replication, RNA transcription, Protein synthesis, Gene and Genome structure and Regulatory mechanisms. Genome-wide approaches and networks aspects should be understood at the introductory level.
- Oggetto:
Results of learning outcomes
Backgrounds in Molecular Biology and Functional Genomics should allow students to read, interpret and comment on recent data of the literature in the fields of Genomics, Functional genomics, transcriptional/post-transcriptional regulatory networks and signalling pathways.
- Oggetto:
Program
- 1. Basic genetics and molecular biology
- a. DNA replication
- b. Transcription
- c. RNA processing
- d. Translation
- e. Molecular localization and dynamics
- 2. Basic genomics
- a. comparative organization of genes and genomes
- b. eukaryotic genomes
- c. vertebrate genomes
- d. coding and noncoding sequences
- 3. Regulatory genomics
- a. nucleosomes and chromatin dynamics
- b. epigenetic regulation and imprinting
- c. centromeres, telomeres, chromatin boundaries
- d. control pathways and transcription factors
- e. coactivator and corepressor complexes in transcription
- f. miRNA, siRNA and other nonclassical regulators
- 1. Basic genetics and molecular biology
Suggested readings and bibliography
- Oggetto:
Genomes 3
T. A. Brown
Ed Italiana Edises Napoli
- Oggetto:
